2. How to Use Anti-rheumatoid Drugs Including Methotrexate (MTX)
نویسندگان
چکیده
منابع مشابه
Albumin-coupled methotrexate (MTX-HSA) is a new anti-arthritic drug which acts synergistically to MTX.
OBJECTIVE To evaluate the anti-arthritic effects of the new inflammation-targeted drug MTX-HSA and to investigate whether peripheral blood mononuclear cells (PBMC) are potential target cells for albumin-mediated drug delivery. METHODS The murine model of collagen-induced arthritis (CIA) was used to measure the anti-arthritic effect of MTX, MTX-HSA or a combination of both (n = 30 to 35 per gr...
متن کامل[How to effectively use methotrexate in rheumatoid arthritis?].
Methotrexate (MTX) is the first choice disease modifying anti-rheumatic drugs for rheumatoid arthritis. In spite of its generalized use by rheumatologists worldwide, there is a general lack of agreement regarding the route of administration, the start-up dose and the way to increase the same. In this article we propose a simplified outline for the use of the drug that should be individualized, ...
متن کاملTreatment of methotrexate (MTX) intolerance: behavioural therapy, versus switch to parenteral MTX versus oral MTX
Methods 45 JIA patients with MTX intolerance were randomised to receive oral MTX with anti-emetics (standard of care), parenteral MTX or oral MTX with behavioural therapy. Primary outcome was the occurrence of MTX intolerance, defined as ≥5 points on a validated MISS questionnaire, after a 3-month intervention period. Secondary outcome measures were: MTX intolerance after 6 and 12 months and th...
متن کاملEfficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis
OBJECTIVE To evaluate the efficacy and toxicity of methotrexate (MTX) monotherapy compared with MTX combination with non-biological disease-modifying antirheumatic drugs (DMARDs) in adults with rheumatoid arthritis. METHOD A systematic review of randomised trials comparing MTX alone and in combination with other non-biological DMARDs was carried out. Trials were identified in Medline, EMBASE,...
متن کاملHow to Use Glutaraldehyde
الهای متمادی است که سرویس های بهداشتی گلوتار آلدئید را بعنوان یک ماده استریل کننده برای وسایلی که نسبت به گرما حساس هستند مورد استفاده قرار می دهند. همزمان با افزایش تقاضا برای استفاده از اندوسکوپی، استفاده از گلوتار آلدئید و تماس با آن نیز افزایش یافته است. باید خاطر نشان ساخت گلوتار آلدئید می تواند سبب ایجاد حساسیت های پوستی، چشمی و تنفسی گردد که نهایتاً امکان دارد این حساسیت به آسم و رنیت آل...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2009
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.98.2493